The frequency of DCTN1 rare variants in sporadic ALS was 0.39% (2 of 510), lower than the data previously reported in sporadic ALS in Japanese (1.07%, 5 of 469)[9], American (2.07%-2.87%, 5 of 242, 10 of 349)[6, 7]and Irish (0.51%, 2 of 394)[8]. Here, DCTN1 is linked to amyotrophic lateral sclerosis.