LMP1 also induces c-Myc-mediated trans-activation of the hTERT promoter in primary human nasopharyngeal epithelial cells and in a nasopharyngeal carcinoma cell line, while inhibition of LMP1 is associated with telomerase downregulation and induction of apoptosis in EBV-positive lymphomas [100,101]. This evidence concerns the gene PDLIM7 and nasopharyngeal carcinoma.