Still, mRNA levels of Hcn2, β2-adrenergic receptor, and Bnf, a thyroid hormone-dependent ventricular hypertrophy marker, were raised, along with severe bradycardia, concluding that thyrotoxicosis may have pathological consequences that could continue ahead of the serum T4 level recovery [21]. The gene discussed is HCN2; the disease is Ventricular hypertrophy.