Recently, Tsou et al. [52] have found that increased expression of angiogenic chemokines, such as growth-regulated protein-γ (Gro-γ/CXCL3) and granulocyte chemotactic protein 2 (GCP-2/CXCL6) in serum and endothelial cells obtained from SSc patients, was unable to induce angiogenesis. The gene discussed is CXCL6; the disease is systemic sclerosis.