TSLP and Alzheimer disease: Of further interest, TSLP released from challenged keratinocytes (31–35) would play an important role in the disease by contributing to the itch symptoms that characterize the disease (42) but also to the Th2-promoting conditions (43–47), thus favoring inflammation and thereby also barrier alterations (48), playing thereby a potentially initiating role in the vicious circle of AD pathogenesis.