Interestingly the Th1 response to T. gondii was not diminished in CD4+ and CD8+ T cells in co-infected animals, since both subsets were able to produce similar amounts of IFN-γ in contrast to other studies, where the helminth infection precedes the protozoan infection (Khan et al., 2008; Marple et al., 2017). The gene discussed is CD4; the disease is helminthiasis.