To analyze the relevance of miR-27a-5p induction in a pathological context, we cocultured under transwell condition resting NK cells and the prototypic SH-SY5Y NB cell line, which we described to induce a TGF-β1-mediated downregulation of CX3CR1 surface expression (12). This evidence concerns the gene CX3CR1 and neuroblastoma.