Consistently, lectin (HHA)-resistant DENV which lacks both N-glycosylation sites on E protein failed to infect DC-SIGN(+) DC, in contrast to productive infection and replication in DC-SIGN(-) and carbohydrate-independent cells such as Vero, Huh7, C6/36 and Baby Hamster Kidney fibroblasts (BHK-21) (Alen et al., 2012). The gene discussed is CD209; the disease is infection.