In the present study, we examined plasma levels of eight cardiac-related or atherosclerosis-related lncRNAs, including H19, long intergenic non-coding RNA predicting cardiac remodeling (LIPCAR), APOA1-AS, THRIL, HULC, SLC26A4-AS1, LincRNA-Cox2, LincRNA-p2111–15, 19–22, in patients with angiographically demonstrated CAD to investigate the possibility of these circulating lncRNAs as novel biomarkers for CAD. This evidence concerns the gene H19 and atherosclerosis.