CCN2 and Hypertension: Genistein obtains high scores with context information because it is connected to hypertension across body parts through its target in CODA: genistein affects FGF1 in fibroblasts in skin, FGF1 in fibroblasts in skin affects FGFR1 in muscle cells in myocardium, FGFR1 is associated with UBC in muscle cells in myocardium, UBC is associated with CTGF in muscle cells in myocardium, and finally CTGF is associated with hypertension in muscle cells in myocardium (Fig. 7b).