NBS-iPSCs can also provide a screening system for treatments which might increase the life span and quality of life of patients with NBS and similar diseases like Fanconi Anemia (FA), Ligase IV (LIG4) syndrome, Bloom syndrome, NBS-like disorder, ataxia-telangiectasia-like disorder (ATLD), Nonhomologous end-joining factor 1 (NHEJ1) syndrome and Seckel syndrome, which all derive from mutated genes in repair pathways55, 56. Here, NHEJ1 is linked to Friedreich ataxia.