NBS-iPSCs can also provide a screening system for treatments which might increase the life span and quality of life of patients with NBS and similar diseases like Fanconi Anemia (FA), Ligase IV (LIG4) syndrome, Bloom syndrome, NBS-like disorder, ataxia-telangiectasia-like disorder (ATLD), Nonhomologous end-joining factor 1 (NHEJ1) syndrome and Seckel syndrome, which all derive from mutated genes in repair pathways55, 56. The gene discussed is NHEJ1; the disease is Bloom syndrome.