NHEJ1 and Nijmegen breakage syndrome: There are several diseases like NBS which derive from mutated genes in repair pathways, examples of these include Fanconi Anemia (FA)16, Ligase IV (LIG4) syndrome17,Bloom syndrome18,NBS-like disorder19, Ataxia-Telangiectasia-Like Disorder (ATLD)20, Nonhomologous end-joining factor 1 (NHEJ1) syndrome21 and Seckel syndrome22.