This is a groundbreaking study in there has never been a study prior to their publication that addressed “cardiovascular relaxation and recovery of homeostasis in CAD patients.” Jia et al. [44] found a decrease of perforin and granzyme B expressions accompanied by decreased levels of pro-inflammatory cytokines and stress hormones in 20 patients diagnosed with COPD indicating some of the potential health benefits of SY for individuals living with COPD. Here, PRF1 is linked to coronary artery disorder.