In the meantime, results from clinical trials using Food and Drug Administration (FDA) approved anti-Vascular Endothelial Growth Factor (VEGF) drugs, such as Bevacizumab (Avastin) and Ranibizumab (Lucentis), have been reported as promising means to improve visual acuity and maintain retinal anatomy in patients associated with intraocular microvascular complications, such as diabetic retinopathy, retinal vein occlusion, and AMD [22,23]. This evidence concerns the gene VEGFA and diabetic retinopathy.