THP-1 cells infected with dengue virus induced elevated levels of dengue hemorrhagic fever (DHF)-associated immunomediators such as interleukin (IL)-6, IL-8, interferon γ-induced protein-10 (IP-10), tumor necrosis factor alpha (TNFα) or IFNγ [36]. This evidence concerns the gene CXCL8 and Dengue hemorrhagic fever.