Primary tumors with Chromogranin A expression were larger (mean 21.5 ± 24.9 cm3 versus 18.0 ± 15.4 cm3; p = 0.821) and the tumor burden of a Chromogranin A positive metastasizing component was higher for mean total size and number of metastases (36.4 ± 49.4 mm versus 19.4 ± 31.7 mm; p = 0.458 and 5.3 ± 6.9 versus 3.3 ± 3.4; p = 0.279) (Table 2); however, these differences were not statistically significant. The gene discussed is CHGA; the disease is neoplasm.