Sequencing of 197 cancer-related genes identified the presence in OVDM1-P3 of five SVs: one frameshift deletion (NOTCH2), a variant in the splicing site (MSH2), and three exonic non-synonymous SNVs/mutations (in PBRM1, RUNX1, HNF1A) in addition to 63 exonic non-synonymous SNVs common for OVDM1-P3 and MT1 (Table 2 and S1 Table). The gene discussed is PBRM1; the disease is cancer.