PDZD4 and cancer: Sequencing of 197 cancer-related genes in MT1 revealed one frameshift deletion (in TP53) and four exonic non-synonymous SNVs/mutations (DPYD, NOTCH1, GRP, PDZD4) present in MT1 only compared with OVDM1-P3 and P30 (Table 2 and S1 Table).