Encouragingly, the significantly slower R2* values determined at 3T in the tumours arising within the Th-ALKF1174L/Th-MYCN mice is wholly consistent with their impaired haemodynamic vascular phenotype relative to that in the Th-MYCN mice, previously established using intrinsic susceptibility MRI at 7T (Jamin et al, 2014), supporting the concept of ‘MRI genotyping’ in vivo (Nieman et al, 2007). Here, MYCN is linked to neoplasm.