Additionally, our findings also differ from Aβ PET imaging study showing elevated Aβ in 50% of participants with iNPH [22], an autopsy study showing 56% comorbid AD pathology when obtained from multiple brain areas [34] and another study showing 68% of comorbid AD measured by phosphorylated tau and amyloid beta ratio in ventricular CSF [21], which all could be a results of biopsy samples being obtained during shunt surgery only from one area, thus resulting possibly in under diagnosis. Here, MAPT is linked to Alzheimer disease.