To investigate whether Axl plays a crucial role in ZIKV infection in mice, newbornAxl−/− and Axl+/− mice generated fromAxl−/− x Axl+/− were characterized bygenotyping PCR (Fig. S1, available in the online Supplementary Material) and wereinjected intracerebrally with 100 pfu ZIKV (CAS-ZK01 strain) within 72 hafter birth. This evidence concerns the gene AXL and Zika virus infectious disease.