SLC12A5 and juvenile myoclonic epilepsy: Along this line, KCC2-pHext, was previously used to characterize the surface expression of KCC2 mutants associated with human idiopathic generalized epilepsy (Kahle et al., 2014) and describe the functional significance of KCC2’s Thr906 and Thr1007 phosphorylation sites (Friedel et al., 2015).