However, these antibodies may be found in patients with systemic lupus erythematosus, rheumatoid arthritis, or MG.11,12 LEMS has also been associated with other araneoplastic autoantibodies including CRMP-5; anti-glutamic acid decarboxylase antibodies; anti-neuronal nuclear antibody, type 1 (Hu); anti-neuronal nuclear antibody, type 2 (Ri); anti-glial nuclear antibody, type 1 (AGNA1, Sox1); amphiphysin antibody; and Zic4.13, , , , -18. This evidence concerns the gene ZIC4 and myasthenia gravis.