LACTB and neoplasm: Quite stunning recent findings are that PE with arachidonic acyl chains is a target of lipoxygenase, which oxidizes the unsaturated acyl chains into cytotoxic lipid hydroperoxides that promote ferroptosis [57]; PE is the target of a plant natural product that has potent anticancer activity [58], and the mitochondrial protein LACTB is a tumor suppressor that targets PSD for degradation [59].