Indeed, EMT was observed in both JAM-A-transfected B-lymphoma cells (P = 0.0025, P = 0.0046 and P = 0.0171, Fig. 3A) and the tumor samples of DLBCL patients with high JAM-A expression (P = 0.0048, P = 0.0126 and P = 0.0101, Fig. 3B). This evidence concerns the gene F11R and diffuse large B-cell lymphoma.