Ectopic expression of JAM-A stimulated lymphoma cell colony formation (P = 0.0354 and P = 0.0398, Fig. 2B) and induced higher expression of cancer stem-cell marker CD133 and CD34 than those of control vector (Vector) (P = 0.0003 and P = 0.0061 for CD133, P = 0.0197 and P = 0.0250 for CD34, Fig. 2C). This evidence concerns the gene PROM1 and lymphoma.