Firstly, the proportion of cells immunopositive for LOX-1 and ox-LDL were higher than that of cells from non-degenerated IVDs, and this immunopositivity increased with the severity of degeneration in NPC, endplate cartilage (EPC), and outer annulus fibrosus (OAF). This evidence concerns the gene OLR1 and nasopharyngeal carcinoma.