UMOD and autosomal dominant medullary cystic kidney disease with or without hyperuricemia: Five ADTKD genes have been identified so far: UMOD (16p12)2, MUC1 (mucin 1, 1q21)3, HNF1B (HNF1beta, 17q12)4, REN (renin, 1q32)5 and SEC 61A1 (Sec 61 translocon alpha 1 subunit, 3q21)6.