FOXM1 and central nervous system cancer: To further characterize the association of MYBL2 and FoxM1with glioma survival, we analyzed the interaction of MYBL2 and FoxM1 with radiotherapy status in HGG cohorts of TCGA, and observed that compared to patients with MYBL2 over-expression and radiotherapy, those with MYBL2 over-expression but without radiotherapy had a significantly higher death risk (adjusted HR = 5.29, 95% CI = 1.475–18.969, P < 0.05) (Tables 6 and 7).