The TNFAIP3 polymorphism rs2230926, a nonsynonymous common coding single-nucleotide polymorphism (SNP) in exon 3 of TNFAIP3, has been shown to possibly influence the mRNA expression of TNFAIP3 and the function of TNFAIP3 and to be associated with autoimmune disorders such as systemic lupus erythematosus [19, 20]. This evidence concerns the gene TNFAIP3 and systemic lupus erythematosus.