Toth et al. found that the levels of platelet (CD61-positive), activated platelet (platelets which have undergone degranulation and are CD62P- and CD63-positive), endothelium-derived (CD62E-positive), leukocyte (CD45-positive) and TF-bearing (CD142-positive) microvesicles as well as the total amount of Annexin V - positive microvesicles correlate with tumor size in breast cancer patients [15]. Here, ANXA5 is linked to neoplasm.