Moreover, patients with G3 soft tissue sarcoma (n = 9) presented with higher levels of Annexin V-positive and endothelium-derived (CD62E-positive) microvesicles compared to patients with G2 soft tissue sarcoma (n = 8) (p = 0.0483 and p = 0.0045). This evidence concerns the gene ANXA5 and soft tissue sarcoma.