The total amount of Annexin V-positive microvesicles as well as leukocyte (CD45-positive) and endothelium-derived (CD62E-positive) microvesicles were significantly higher in patients with G3 soft tissue sarcoma (n = 9) compared to healthy controls (n = 17) (p = 0.0304, p = 0.0254 and p = 0.0357, respectively; Fig. 2). The gene discussed is ANXA5; the disease is soft tissue sarcoma.