Theander and Mandl [15] recruited 105 patients with pSS and, using a simplified SGUS scoring system, showed that patients with a more severe SGUS score had a higher frequency of autoantibodies (anti-Ro/SSA and anti-La/SSB, ANA, and rheumatoid factor) and significantly higher levels of IgG than patients with normal SGUS findings. This evidence concerns the gene SSB and peeling skin syndrome.