Previous studies have reported that the activation of HSF1 promoted the growth of hepatocellular carcinoma by stimulating lipid biosynthesis and activating the nuclear factor kappa B (NF‐κB) signaling pathway and mitogen‐activated protein kinase (MAPK) signaling pathway (Chuma et al., 2014; Jin et al., 2011). Here, NFKB1 is linked to hepatocellular carcinoma.