Consistent with this data, immunofluorescence analyses for p110β and ErbB2 on tumor sections, revealed similar co-localization of p110β and ErbB2 across genotypes, confirming that p110β recruitment to the ErbB2/ErbB3 heterodimer is not increased in p110α-deficient tumors (n=7 for each genotype) (figure 4c). This evidence concerns the gene ERBB3 and neoplasm.