TP53 and cervical carcinoma: We provided evidence that apoptotic wild-type p53 HeLa cells (harboring integrated HPV18) and Ca Ski cells (derived from a metastatic cervical epidermoid carcinoma harboring integrated HPV16) but not p53-mutated and HPV-negative C-33 A cells (derived from a rare HPV-negative cervical carcinoma) were able to transform human primary fibroblasts (HPFs) [40,42].