miR-200s promoted metastatic colonisation of breast cancer cells through its gene target Sec23 (S. Cerevisiae) Homolog A (SEC23A). In addition, we have also reported that miR-200 families are androgen-responsive as mentioned [39], suggesting that AR have a role for activating these miRNAs and promotes prostate cancer cell proliferation. Here, SEC23A is linked to Familial prostate cancer.