Through the collection of saliva and plasma samples from 250 individuals with a prior history of cardiovascular disease, salivary levels of CRP, prostaglandin E2 (PGE2), leukotriene B4 (LTB4), matrix metaaloproteinase 9 (MMP9), creatinine and lysozyme were measured, with the results indicating that saliva could be an alternative means for evaluation of cardiovascular risk [18]. This evidence concerns the gene MMP9 and cardiovascular disorder.