Expression of Cryab has been found to be higher in tongue carcinoma compared with normal Ctrl tissue 32, overexpression of Cryab was found to be protective in retinal epithelial cells against stress‐induced apoptosis 33, while at gene expression level, the amount of α‐, β‐ and γ‐crystallin increased in the retina after injury 34, 35, 36. The gene discussed is CRYAB; the disease is tongue cancer.