In line with the hepatic fibrogenesis in HFrD-fed A/AHep mice, there was strongly increased expression of liver fibrosis marker genes (Col1A1, Col3A1, Timp1 and Pdgfr-β) in the livers of the HFrD-fed A/AHep mice. The gene discussed is COL3A1; the disease is Hepatic fibrosis.