ERBB2 and cancer: The UK has taken a pragmatic approach to patient selection for partial-breast radiotherapy by producing a consensus statement,32 which states that partial-breast radiotherapy can be considered for patients who are 50 years or older, with grade 1–2 cancer, a tumour of 30 mm or less, ER positive, HER2 negative, and N0 with minimum 1 mm radial excision margins for invasive disease.