In addition, we analyzed PON1 activity in connection with HDL-C and apoAI levels in the sera of CAD patients and N subjects, and found a positive correlation between HDL-C or apoAI levels and PON1 activity (r = 0.273, p = 0.004 and r = 0.221, p = 0.013, respectively) (Figure S1a, S1b). This evidence concerns the gene APOA1 and coronary artery disorder.