PON1 and coronary artery disorder: PON1 protein levels in patients’ sera followed the same trend as HDL-C and apoAI levels, with a statistically significant decrease in all CAD patients versus N subjects (SA, 12%, p = 0.047; ACS, 23%, p = 0.0004), and also in ACS compared to SA (13%, p = 0.049) (Fig. 1a).