The ratio between MPO protein and PON1 activity was significantly higher in ACS versus SA and N (85%, p = 0.014, and 280%, p = 0.0008, respectively); the ratio of MPO protein to PON1 protein was also increased in CAD patients versus N subjects (SA, 56%, p = 0.012, and ACS, 120%, p = 0.00016), and in ACS versus SA (42%, p = 0.023) (Fig. 1f). This evidence concerns the gene MPO and coronary artery disorder.