Because the urine glucose concentration of normal adults ranges from 0.002% to 0.02% (2–20 mg/dL) and that in people with diabetes is higher than 3.14% (3140 mg/dL) (http://www.urinemetabolome.ca/), Crp inactivation might be biologically significant, leading to increased kidney colonization and subsequent infection in patients with diabetes. Here, CRP is linked to diabetes mellitus.