Among the introgressed indels that were present in both Europeans and East-Asians and that scored highest for affecting phenotype we found a frame shift insertion in PTCHD3 (patched domain-containing protein-3), a gene which has a role in sperm development or sperm function [40] and that has been found to contain a risk-allele for asthma [41]. This evidence concerns the gene PTCHD3 and asthma.