TYR and melanoma: Tuerxuntayi et al. [46] of our group reported that Kaliziri increased the tyrosinase activity and melanin content in a dose-dependent manner at concentrations of 5–40 μg/mL, and treatment with 20 μg/mL Kaliziri extract (KZE) enhanced the expression of tyrosinase in B16 melanoma cells in a time-dependent manner.