Looking at the large differences in cellular growth of highly proliferative Caki-1 and 786-O and lowly proliferative RCC4 and A498 cell lines, however, classification of TNFSF13B as a proliferative factor in RCC, as has been done in previous studies [17], could not be clearly confirmed. The gene discussed is TNFSF13B; the disease is renal cell adenocarcinoma.