However, two cases of lymphoid tumours (more than 80% clonal based on TCR rearrangements (Supplementary Figure S4)) were previously found in a cohort of aged Smug1tm1a(EUCOMM)Hmgu−/−Ungtm1Tld−/− mice (hereafter referred to as UNG/SMUG1-DKO) at about 2 years of age12. The gene discussed is UNG; the disease is lymphoid neoplasm.