In addition, we evaluated the cell surface expression of the urokinase plasminogen activator receptor (uPAR) and integrin beta-1 (int-β1), two markers which have been directly implicated in breast cancer dormancy and reactivation both in vitro and in vivo, and compared the expression of Ki67 vis-à-vis uPAR/int-β1 to check whether they corroborated with each other10, 34, 35. Here, ITGB1 is linked to breast cancer.