In our previous report we had demonstrated that sequences derived from the junction region (a.a. 251–280) of EWS-FLI1 protein when expressed in Ewing’s sarcoma cells inhibited their tumorigenic properties, and affected epithelial to mesenchymal transition (EMT) markers and EWS-FLI1 target genes expression8. The gene discussed is EWSR1; the disease is Ewing sarcoma.