2002). Several studies have suggested that inhibition of UA production by a xanthine oxidase (XO) inhibitor, allopurinol, is a potential therapeutic option in the treatment and management of a variety of kidney diseases (Kang et al. 2002; Nakagawa et al. 2003; Feig et al. 2008; Kosugi et al. 2009). The gene discussed is XDH; the disease is kidney disorder.