For instance, Huntington’s disease is caused by expansion of the polyglutamine stretch beyond 35 repeats, in the protein Huntingtin, resulting in striatal and cortical neuronal cell death [5], while Spinocerebellar Ataxia 17 is caused by mutations of a stretch of more than 42 polyglutamines in the general transcription factor, TATA-binding protein, resulting in loss of cerebellar neurons [6]. The gene discussed is ABT1; the disease is spinocerebellar ataxia type 17.