Finally, a recent article identified an association of a novel homozygous mutation in Sec23 homolog A (SEC23A) gene and a previously reported homozygous mutation in mannosidase alpha class 1B member 1 (MAN1B1) gene in two patients, from a consanguineous family of Lebanese origin, presenting somatic overgrowth, macrocephaly, mild dysmorphic features, hypertelorism, maloccluded teeth, intellectual disability and flat feet [38]. Here, MAN1B1 is linked to Intellectual disability.