By contrast, rats in the Fin- and PFE-treated groups (0.30 ± 0.13 and 0.35 ± 0.16, P < 0.01 and P < 0.05, respectively) exhibited a significantly reduced relative ratio of PCNA/β-actin compared with rats in the BPH group (Fig. 7b). Here, PCNA is linked to benign prostatic hyperplasia.