A ChIP-Seq study of H3K4me2 in naïve and memory CD4+ T cells obtained from 12 asthma patients and 12 healthy controls found that H3K4me2-marked enhancers were associated with both asthma susceptibility and Th2 cell type, and that asthma GWAS SNPs were enriched in the Th2 enhancers [154]. Here, CD4 is linked to asthma.